Head of Microbiota Lab
Full Professor
room 2.02 Faculty of Pharmacy
Contact: sebastian.granica(at)wum.edu.pl
tel. +48 22 5720953
Publications
►Scopus ►ORCID ►Google Scholar
Teaching
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Laboratory courses in microscopic identification of plant materials for third-year students of Pharmacy.
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Laboratory courses in phytochemistry for third-year students of Pharmacy.
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Pharmacognosy seminars for third-year students of Pharmacy
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Laboratory courses in phytochemical preparation for fourth-year pharmacy students as part of the specialization blocks Phytochemistry and Phytotherapy, and Analytical Pharmacy.
Research
The research is focused on the analysis of the chemical composition of plant materials used traditionally in various diseases. Apart from that, the bioactivity of raw extract from investigated plant materials and their constituents in several cell-based models are performed. Recently, several projects focused on interactions of plant extracts with human microbiota, gut and skin microbiota, were established. The changes in the chemical composition and bioactivity of extracts after incubation with microbiota are investigated in the Microbiota Lab research group.
Education
02.2021- now
Full Professorship in Medical and Health Sciences, discipline: pharmaceutical sciences
07.2016 -01.2021
Habilitation in Pharmacy
Medical University of Warsaw, Faculty of Pharmacy, Department of Pharmacognosy and Molecular Basis of Phytotherapy. Area of research: Phytochemical analysis of polyphenols and monoterpenoids occurring in chosen plant materials belonging to Asteraceae, Rosaceae and Polygonaceae families.
2010-2014
Ph.D.
Medical University of Warsaw, Faculty of Pharmacy, Pharmacy.
Thesis mentored by prof. dr hab. n. farm. Anna K. Kiss. Area of research: Phytochemical analysis, evaluation of antioxidant and anti-inflammatory properties of chosen plant materials belonging to the evening primrose family (Oenotheraceae)
2006-2011
M.Sc.
University of Warsaw, Faculty of Chemistry, Chemistry.
Thesis mentored by prof. dr hab. n. chem. Zbigniew Czarnocki. Area of research:
2004-2010
M.Sc.
Medical University of Warsaw, Faculty of Pharmacy, Pharmacy.
Thesis mentored by prof. dr hab. n. farm. Anna K. Kiss. Area of research:
Scientific experience
2016/2017 two short term internships at the Institute of Pharmacognosy, University of Innsbruck
2015 four short term scientific internships (one week each) at the Institute of Biomolecular Chemistry (ICB), CNR, Pozzuoli, Naples, Italy
10.2013-04.2014 6-months internship in Institute of Pharmacognosy, University of Innsbruck; supervisor: prof. Christian Zidorn
08.2011 HPLC-MS training, Bruker Daltonics, Bremen, Germany
09.2008 4-weeks practice in the Department of Plant Biochemistry, Faculty of Biology, the University of Warsaw under the supervision of prof. Wirginia Janiszowska
Basic research projects
Since 10.2021 principal investigator in Polish National Science Centre Preludium Bis Grant No 2020/39/O/NZ7/01109; ‘Interactions of plant extracts traditionally used in skin diseases with a human skin microbiota, 2021-2025
since 01.2019 principal investigator in Polish National Science Centre Opus Grant No 2018/29/B/NZ7/01873; ‘Do natural products of plant origin support the therapy of urinary tract infections (UTIs)?, 2019-2022
02.2016-01.2020 principal investigator in Polish National Science Centre- Sonata Grant No 2015/17/D/NZ7/02641; ‘Phytochemical analysis and evaluation of anti-inflammatory and antimicrobial activities of extracts prepared from pharmacopoeial plant material lime flower (Tiliae flos).’, 2016-2020
04.2014-05.2016 principal investigator in Polish Ministry of Science project – Iuventus Plus Grant No IP2012 012972; ‘Isolation and quantification of major polyphenolic constitutes of pharmacopoeial plant material – Polygoni avicularis herba”, 2014-2016
07.2013-07.2015 principal investigator in Polish National Science Centre- Preludium Grant No 2012/07/N/NZ7/01136; ‘The influence of chosen ellagitannins on functions of human neutrophils the context of prevention and treatment of oral cavity diseases, 2013-2015
06.2012-06.2014 participation as investigator in Polish National Science Centre- Preludium Grant No 2011/03/N/NZ7/01785; ‘Influence of gut flora-derived ellagitannins' metabolites- urolithins on the pro-inflammatory activity of neutrophils in connection with cardiovascular disease.’ 2012-2014
06.2012-12.2013 principal investigator in the young scientists' grant in the Faculty of Pharmacy, Medical University of Warsaw 2012/2013 No FW25/PM31D/12; ‘Isolation and identification of major polyphenolic constituents of Circaea lutetiana herba’
Applied research projects
2021
Principal investigator/project manager. Innovative cream improving skin microbiota condition Incubator of Innovation 4.0, Polish Ministry of Science and Higher Education grant FW251/FS249.
2018-2019
Principal investigator/project manager. Active natural products from olive oil (OLC) for topical application in the treatment of inflammations of skin and mucosa Incubator of Innovation 2.0, Polish Ministry of Science and Higher Education grant FW25/200.
Scholarships and awards
21.10.2020
Gold Medal at International Warsaw Invention Show for the invention Urolithin A and its composition for external use in inflammations of various etiologies.
2019-2022
Scholarship of the Polish Minister of Science and Higher Education for outstanding young researchers.
09.2017
Bionorica Phytoneering Award for the achievements in the research on the bioactivity of ellagitannins and their gut microbiota metabolites awarded by Society for Medicinal Plant and Natural Product Research and Bionorica.
2016-2017
START Scholarship for Young Scientists, Foundation for Polish Science.
2015
Planta Medica journal award for the Most Innovative Paper published in 2014.
2013
Scholarship of the Polish Ministry of Science and Higher Education for the best Ph.D. students.
2012-2020
Medical University of Warsaw Rector Scientific Awards.